Southampton vs. Manchester United
The Premier League kicks off with an exciting clash as Southampton host Manchester United at St. Mary's Stadium. Southampton will be looking to capitalize on their home advantage, with a 50 percent win rate in their last two matches on home turf. On the other hand, Manchester United will be aiming to secure a positive result to climb up the league standings.
Brighton vs. Ipswich Town
Brighton will face off against Ipswich Town at The American Express Community Stadium. Ipswich Town have been struggling away from home, losing 100 percent of their last away match in the Premier League. Brighton will see this as an opportunity to continue their strong form and secure crucial points.
Crystal Palace vs. Leicester City
Crystal Palace welcomes Leicester City to Selhurst Park in a significant fixture where both teams are level on points in the standings. Crystal Palace will be hoping to break their deadlock as they have drawn 50 percent of their last six head-to-head matches against Leicester City. Leicester City, on the other hand, will be aiming to turn around their form, having lost 100 percent of their last away matches in the league.
Fulham vs. West Ham
Fulham and West Ham will clash at Craven Cottage in a mid-table battle. Fulham currently sit just above West Ham in the standings and will be looking to extend their lead. West Ham, with one away win this season, will be eager to secure a victory and close the gap on Fulham.
Liverpool vs. Nottingham Forest
Anfield will be the stage for the match between Liverpool and Nottingham Forest. Liverpool holds the upper hand in head-to-head stats, with three wins in their last four encounters in the league. Nottingham Forest, however, have been impressive away from home this season, winning both of their away matches. Liverpool will need to be at their best to secure the three points.
Manchester City vs. Brentford
League leaders Manchester City will take on Brentford at the Etihad Stadium. Manchester City have dominated the head-to-head matchups, winning four out of their last six encounters against Brentford. Brentford, sitting in sixth place, have been in good form with two wins in their last three away matches in the league.
Aston Villa vs. Everton
Aston Villa will square off against Everton at Villa Park in what promises to be a thrilling encounter. Aston Villa has a strong record in recent head-to-head matches, winning four out of their last six encounters across all competitions. Everton, however, have struggled on the road, losing 100 percent of their last two away matches in the Premier League.
Bournemouth vs. Chelsea
Bournemouth will face a tough test against Chelsea at the Vitality Stadium. Bournemouth have had a mixed record in head-to-head matchups, losing 50 percent of their last six encounters in the Premier League. Chelsea, on the other hand, have been solid away from home, winning their last away match in the league.
Tottenham vs. Arsenal (North London Derby)
The North London Derby takes center stage as Tottenham Hotspur host Arsenal at Tottenham Hotspur Stadium. Tottenham will be looking to improve their recent record in the derby, having lost 67 percent of their last six head-to-head matches in the Premier League. Arsenal, on the other hand, come into the match in fine form, with two wins in their two away matches in the league and five wins in their last six matches overall.
Wolverhampton vs. Newcastle United
The round concludes with Wolverhampton facing Newcastle United at Molineux Stadium. Wolverhampton will be aiming to bounce back from their recent home struggles, having lost their last two home matches in the Premier League. Newcastle United, meanwhile, have been in impressive form, winning 83 percent of their last six league matches.